Beyond CRISPR: TALEN, smart cells, and the regulatory edge in gene editing

Cell & Gene Therapy Insights 2025; 11(7), 815–821

DOI: 10.18609/cgti.2025.091

Published: 9 September
Interview
David Sourdive



“Success in gene editing is not only about having strong backbones or optimizing specificity, it is also about delivering these tools in a way that ensures performance and precision.”

In this discussion, Abi Pinchbeck, Editor, Cell & Gene Therapy Insights, speaks to David Sourdive, Executive Vice President, CMC & Manufacturing, Cellectis, who shares insights into the company’s pioneering work in gene editing and allogeneic CAR-T cell therapies. With considerations surrounding the regulatory CMC space, they explore how smart cell innovation is shaping the future of gene editing.