Enabling early AAV characterization: the role of mass photometry in upstream process development

Tuesday 08:00 PDT / 11:00 EDT / 16:00 BST / 17:00 CEST

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Enabling early AAV characterization: the role of mass photometry in upstream process development

Live30 webinars are thirty-minute presentations designed to update you on the latest innovations, applications, and data in a fast yet interactive format.

Mass photometry is a rapid, cost-effective, and user-friendly technique for AAV characterization that offers a powerful alternative to traditional methods. Mass photometry directly measures molecular mass and provides clearer insights into viral particle populations. In this webinar, find out how mass photometry can be seamlessly integrated early in AAV process development, delivering real-time insights for improved process control and faster decision-making. In addition, advances in purification techniques have enhanced AAV sample compatibility with mass photometry.

This session will highlight how integrating mass photometry as an at-line tool can enable faster, more cost-effective, and scalable analysis of AAV samples, allowing teams to make informed decisions earlier in development. Attendees will see pre- and post-cleanup case study data provided by Refeyn’s collaborators, Généthon and Rentschler, in addition to mass photometry-supported data on the screening of transfection conditions.

Discover new upstream AAV sample cleanup methods that help make mass photometry a practical upstream process monitoring tool
Learn how to overcome the limitations of traditional characterization methods (e.g., AUC, SEC-MALS, TEM) that are slow, impurity-sensitive, and resource-intensive—particularly in early-stage process development
Find out how to implement mass photometry in early development workflows and enhance process monitoring and control strategies, with supporting data

Maria Jacintha Victoria

Market Development Manger (CGT) at Refeyn Ltd.

Jacintha Victoria is a strategic marketing and analytical leader with over a decade of experience in the biotechnology and gene therapy sectors. As the Market Development Manager at Refeyn Ltd. in Oxford, UK, she leads initiatives/ campaigns to drive the adoption of Mass Photometry across critical applications in cell and gene therapy, including AAV, LVV, adenovirus, and RNA-based platforms. With a deep understanding of the emerging analytical technologies, Jacintha advocates for Mass Photometry as a transformative tool to enhance viral vector characterization, accelerate product development, and strengthen regulatory preparedness. She holds a Master of Science in Cellular and Molecular Biology from the University of New Haven and is certified as a Technologist in Molecular Biology by the ASCP. Passionate about bridging science and strategy, Jacintha is dedicated to advancing innovative therapeutic solutions through data-driven marketing, cross-functional collaboration, and thought leadership.

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