Advancing mRNA-LNP characterization: innovative chromatographic approaches for next-generation therapeutics

“No single analytical technique can comprehensively characterize complex biomolecules such as mRNA-LNP products.”

Charlotte Barker (Editor, Vaccine Insights) speaks to Jonathan Maurer (Postdoctoral Researcher, University of Geneva) about critical quality attributes for mRNA-lipid nanoparticle formulations, novel chromatographic methods for integrity and encapsulation efficiency evaluation, and the technical challenges of characterizing large RNA therapeutics.

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