NUCLEIC ACID INSIGHTS

September 2026 Issue

Volume 3 Issue 7

Nucleic Acid Insights Volume 3 Issue 7
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Featuring

Issue Spotlight: Downstream processing and analytics
Other articles
Webinars

SPOTLIGHT

Downstream processing and analytics

Commentary

From precipitation to precision: designing crystallization for oligonucleotide purification

From precipitation to precision: designing crystallization for oligonucleotide purification

Vivek Verma
15 September
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Infographic

Removing the immunogenic dsRNA that standard mRNA purification leaves behind

Removing the immunogenic dsRNA that standard mRNA purification leaves behind

10 September
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Viewpoint

Therapeutic oligonucleotides have come of age: time for analytical technology to catch up

Therapeutic oligonucleotides have come of age: time for analytical technology to catch up

Mike Webb
15 September
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Advancing thermostable mRNA formulations: progress toward cold chain independence

Advancing thermostable mRNA formulations: progress toward cold chain independence

Neha Kaushal
10 September
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Addressing the fill–finish bottleneck for next-generation nucleic acid therapeutics

Addressing the fill–finish bottleneck for next-generation nucleic acid therapeutics

Shrirang Karve
7 September
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articles

Review

Considerations for alternative nonclinical toxicology models for the development of oligonucleotide-based therapeutics

Considerations for alternative nonclinical toxicology models for the development of oligonucleotide-based therapeutics

Jennifer D Sisler, Laura F Michael, Bethany Hannas
15 September
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Innovator Insight

Using humanized liver mice to advance the development of LNP delivery systems

Using humanized liver mice to advance the development of LNP delivery systems

A R Burmeister, S K Donnelly, M Baginski et al.
5 June
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Interview

Fireside chat: building better translational models for mRNA therapeutics

Fireside chat: building better translational models for mRNA therapeutics

Daniella Ishimaru, Joe Cefalu
16 September
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Delivery, delivery, delivery: addressing the remaining challenges in exon skipping for Duchenne

Delivery, delivery, delivery: addressing the remaining challenges in exon skipping for Duchenne

Annemieke Aartsma-Rus
15 September
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White Paper

Oligonucleotide manufacturing efficiency and sustainability: findings from a cross-sector expert meeting

Oligonucleotide manufacturing efficiency and sustainability: findings from a cross-sector expert meeting

Jokūbas Leikauskas, Róisin McGuigan
28 August
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Webinars