Light up your LNP workflow with Sunshine and Stunner AF
Sponsor
Live30 webinars are thirty-minute presentations designed to update you on the latest innovations, applications, and data in a fast yet interactive format.
Problem
From screening early-stage nucleic acid payloads up to GMP-scale production, researchers need tools that grow up with their workflow and keep the process consistent. The perfect production tool needs to be able to grow from small volume, user-friendly runs all the way to multi-parameter, multi-sample, or even large volume, continuous runs. And making lipid nanoparticles (LNPs) is only half the battle— you also need to characterize encapsulation efficiency (EE%), payload quant, size, and PDI. Traditional encapsulation efficiency (EE%) and sizing assays are tedious and each only gives you a single piece of the puzzle, so you still need to juggle multiple instruments for complete characterization.
Solution
Sunshine and Stunner AF (Add Fluorescence) bring together seamlessly scalable nanoparticle production and powerful, all-in-one characterization. Sunshine’s configurable options scale with you – taking you from encapsulating your first payload through multi-sample production and all the way to final process development for GMP. Stunner AF takes the headache out of EE% assays by combining fluorescence for free RNA with UV/Vis for surfactant-free total RNA quantification – and then adds in DLS for sizing, PDI and particle concentration.
Proof
In this webinar, we’ll show how Sunshine and Stunner AF team up to cover the critical steps in LNP development. We’ll use Sunshine to create a variety of LNP formulations from a variety of ionizable and cationic lipids, then measure their performance at encapsulating payloads in a variety of nucleic acid lengths using Stunner AF. You’ll see how this duo helps you hit the ground running with your first gene therapy, reduces hands-on time, and delivers more meaningful data per sample. Whether you’re in academia or scaling to industry, this combo gets your nanoparticle workflow glowing.
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