Scaling viral titers in vaccine manufacturing: from roller bottles to a 10-layer culture vessel

Wednesday 08:00 PDT / 11:00 EDT / 16:00 BST / 17:00 CEST

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Scaling viral titers in vaccine manufacturing: from roller bottles to a 10-layer culture vessel

Live30 webinars pack the latest innovations and applications into a data-rich 30-minute session.

This webinar shares process development data from Vero cell-based vaccine manufacturing, showing how a shift from roller bottles to a high-surface-area, multi-layer culture vessel delivered a 20x increase in viral titer.

The session will cover the practical considerations behind this transition, including surface area, media volume, and operational impact in the cleanroom.

Attend this webinar to:

Review real-world scale-up data from this vaccine manufacturing case study, demonstrating measurable gains in productivity and process efficiency
Understand how increased surface area (up to 6,360 cm² per vessel, versus 850 cm² for a roller bottle) and optimized culture conditions support higher viral titers
Learn how the transition reduced media volume requirements by 15% per cm² while lowering contamination risk
Gain insight into how streamlined vessel handling can reduce cleanroom labor and operational demands during scale-up

Irana Coletti Malaspina

Field Application Scientist at Corning Life Sciences

Irana Coletti Malaspina is a Biologist with a Master’s degree in Industrial Engineering, currently wor

Irana Coletti Malaspina is a Biologist with a Master’s degree in Industrial Engineering, currently working as Field Application Scientist for Corning Life Sciences in the South America Region. Her background is in Advanced Therapy Field with an extensive background in process development for cellular platforms.